Welcome to Dr. Yong Chen's Research Lab!

🌟 Explore the Future of Cancer Research!

At the Chen Lab, we harness the power of bioinformatics and computational systems biology to decode the complexities of cancer. Our mission is to enhance understanding through innovative research methods, focusing on omics studies, chromatin interactions, and the discovery of clinical biomarkers.

In Situ Capture of Chromatin Interactions by Biotinylated dCas9

Cis-regulatory elements (CREs) are commonly recognized by correlative chromatin features, yet the molecular composition of the vast majority of CREs in chromatin remains unknown. Here, we describe a CRISPR affinity purification in situ of regulatory elements (CAPTURE) approach to unbiasedly identify locus-specific chromatin-regulating protein complexes and long-range DNA interactions.

Bioinformatics Innovations

Leveraging computational systems biology for biomarker discovery and precision medicine.

Mathematical Modeling

Applying mathematical models to understand cancer biology and predict therapeutic outcomes.

Omics and Data Integration

Integrating multi-omics data to map molecular pathways involved in cancer and therapeutic resistance.

News & Events

2023-10-15

Breakthrough in Gene Sequencing Algorithm

Our team has developed a new algorithm that significantly reduces the time required for gene sequencing.

2023-10-10

Upcoming Webinar: AI in Bioinformatics

Join us for a webinar discussing the latest applications of AI in bioinformatics research.

2023-10-05

New Research Grant Awarded

Our lab has been awarded a $2M grant to further our research in protein folding prediction.

2023-09-28

Publication in Nature Biotechnology

Our recent paper on CRISPR applications in rare genetic disorders has been published in Nature Biotechnology.

2023-09-20

Collaboration with Pharma Giant

We're excited to announce a new collaboration with a leading pharmaceutical company on drug discovery.